Chiral Screening for SFC and UHPLC 
Produced by Agilent Technologies
This application shows chiral method development for both SFC and UHPLC using the Agilent 1260 Infinity II SFC/UHPLC Hybrid System with software aided method scouting.

Method Transfer of a USP Derived Acetaminophen Assay 
Produced by Thermo Fisher Scientific
This application note demonstrates the transfer of analytical HPLC methods from an Agilent™ 1260 Infinity system to the Thermo Scientific™ UltiMate™ 3000 and the Thermo Scientific™ Vanquish™ platforms.

Reliable GPC/SEC Results by Integrating Chromeleon Software and WinGPC UniChrom 
Produced by PSS
An easy-to-use solution for Chromeleon 7.2 CDS data to be processed in GPC/SEC evaluation mode has been generated by PSS and Thermo Fisher Scientific. This WinGPC solution is available for stand-alone PCs, networked computers or in Client/Server environments. Full compliance with FDA 21CFR part 11 is possible.

Quantification of Host Cell Protein Impurities Using the Agilent 1290 Infinity II LC Coupled with the 6495B Triple Quadrupole LC/MS System 
Produced by Agilent Technologies
This application note demonstrates a workflow for sensitive quantification of host cell proteins. Using a multiple reaction Chiral Screening for SFC and UHPLC monitoring (MRM)-based isotope dilution method, it was shown that HCPs at low sub ppm (ng/mg) levels could be accurately quantified.

Discovery of Biomarkers in Breath: Enhancing Separation and Identification using GC×GC–TOF MS 
Produced by SepSolve Analytical
Study examining the use of thermal desorption tubes for breath sampling, with secondary focusing carried out on the Centri^® sample automation and concentration platform, in conjunction with comprehensive two-dimensional gas chromatography and time-of-flight mass spectrometry (GC×GC–TOF MS).

SMART Digest Peptide Mapping and Quantitation Compendium: Peptide Mapping and Quantitation – Easier, Faster and More Reproducible 
Produced by Thermo Fisher Scientific
Gain consistent confidence in your protein digestion for peptide mapping and quantitation workflows with this application note compendium.

Host Cell Protein Analysis Using Agilent AssayMAP Bravo and 6545XT AdvanceBio LC/Q-TOF 
Produced by Agilent Technologies
This study demonstrates an end to end HCP analysis workflow including the Agilent AssayMAP Bravo for automated sample preparation, 6545XT AdvanceBio LC/Q TOF for LC-MS/MS analysis, and software for data analysis.

Improved Sensitivity for LC-MS Quantitation of Pharmaceutical Compounds in Human Plasma with MicroLC Using a New Microflow Source Design
Produced by SCIEX
This study illustrates the capability of a SCIEX^® QTRAP^® 6500+ LC/MS/MS system with an OptiFlow™ Turbo V Ion Source with SteadySpray™ probe for the quantitation of pharmaceutical compounds using microflow LC.

Analytical Determination of Drugs in Serum Using the Ultivo Triple Quadrupole LC/MS 
Produced by Agilent Technologies
This application note demonstrates a sensitive and precise method for analyzing eight drugs in serum on the Agilent Ultivo triple quadrupole LC/MS system. Excellent method precision was achieved, with relative standard deviations (RSD%) of <10 % at the lowest level of quantitation. Little to no sample prep is require for the Ultivo to achieve sensitive and precise detection of drugs.

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